CXCR3 is a chemokine receptor that is primarily expressed on CD4+ and CD8+ T cells, and to some extent by other cells, among them, epithelial cells.
Chemokines and their receptors play an important role in the recruitment, activation and differentiation of immune cells. The chemokine receptor, CXCR3, and its ligands, CXCL9,
CXCL10, and CXCL11 are key immune chemoattractants during interferon-induced inflammatory responses.
(Source: Karin, 2020;
Kuo, 2018)
